Our Team

  • Mark Chandy

    Principal Investigator

    My research employs molecular biology to understand the pathophysiology of cardiovascular disease using human induced pluripotent stem cells (iPSC)-derived tissue. Advances in next generation sequencing (NGS), proteomics, and gene editing have made it possible to decipher the mechanisms of cardiovascular disease.

  • Aleks Leligdowicz

    Principal Investigator

    My research focuses on studying samples from patients admitted to the Intensive Care Unit with acute infection to understand how heterogeneity in the immune response and endothelial injury contribute to patient outcomes. The goal of my research is to improve our understanding of sepsis pathobiology and identify treatable biological traits.

  • Kerry-Ann Nakrieko

    C3RP Lab Manager

    My prior research has investigated protein trafficking and dermatological health using cell biology and molecular biology techniques. My roles in the C3RP Team are to provide technical and other support to students, help manage the laboratory, perform and summarize experiments, and receive and process clinical research samples.

  • Michelle Si

    C3RP Research Technician

    I prepare and perform experiments using human tissue samples following defined protocols and procedures, and I also provide assistance, training and oversight to students regarding experimental procedures and techniques.

  • Poorna MR

    Postdoctoral Associate

    I am a PhD Graduate in Life Sciences from Amrita Vishwa Vidyapeetham University. My PhD work used human iPSC-derived hepatocytes as an in vitro drug toxicity screening platform. In the C3RP team, my research focuses on investigating the effects of environmental risk factors on the cardiovascular system.

  • Yasamin Minazadeh

    MSc Student

    I am a first-year master's student in Microbiology and Immunology at the Schulich School. I completed my undergraduate in Molecular and Cellular Biology at Azad University of Medical Science, Tehran, Iran. My research focuses on the effects of Macrophages in ARDS.

  • Zina Zein Abdin

    MSc Student

  • Logan Van Nynatten

    Critical Care Medicine Fellow

    I completed medical school at the Schulich School of Medicine at Western University, followed by Internal Medicing residency. I am currently a Critical Care Medicine fellow. My research interests include biomarker development, proteomics and molecular imaging. With the C3RP laboratory, I am characterizing the molecular biology of venous congestion in critical illness.

  • Grace Adetunde

    Clinical trial programme placement

    I am an M.Sc graduate of microbiology and a current postgraduate diploma student in the clinical trial management programme at Western University. In the C3RP laboratory, my research focuses on understanding disease mechanisms using iPSC-disease modelling to identify new biomarkers and potential treatments for cardiovascular disease.

  • Jonathan Moroniti

    SRTP Student

    I am a second-year medical student at the Schulich School of Medicine. I completed undergraduate and Master’s degrees at McMaster in Biomedical Discovery and Commercialization and worked for the Health Economics and Outcomes Research group of a pharmaceutical company. My research focuses on using iPSCs to understand endothelial injury during sepsis.

  • Josephine Liu

    SRTP Student

    I am a first-year medical student at the Schulich School of Medicine. I completed my Bachelor of Health Sciences at Queen’s University, where I studied antibiotic resistance mechanisms. After experiencing septic shock myself, I was inspired to join C3RP to understand sepsis pathophysiology. My research focuses on understanding immune responses in patients with early sepsis.

  • Victoria Labuda

    Honours Specialization student

    I am a fourth-year student in the Medical Sciences program specializing in Microbiology and Immunology with Pathology. I am passionate about translational biology and understanding how dysregulated immune responses contribute to the pathogenesis of disease.

  • Jahin Abrar Kashfi

    Honours Specialization student

    I am a fourth-year undergraduate student in the Medical Sciences program with an Honours Specialization in Physiology and Pharmacology. I am fascinated by stem cell research and cardiology. I am excited to be a part of something meaningful!

  • Andrew Khoury

    Honours Specialization student

    I am a fourth-year student in the Medical Sciences program, studying Microbiology and Immunology. I have spent the last two summers researching oral inflammation and its connection to systemic inflammation at the University of Toronto Faculty of Dentistry. I am now exploring the relationship between immune system dysregulation and endothelial injury during sepsis.

  • Mengqi (Coco) Guo

    Honours specialization student

    I am a fourth-year student in Biochemistry of Infection and Immunity at Western University. My thesis project aims to investigate macrophage function during critical illness using iPSCs. I enjoy photography and binge-watching in my spare time.

  • Harman Thind

    NSERC Undergraduate Student

    I am a third-year Physiology & Pharmacology undergraduate student preparing to become a physician. I am interested in regenerative medicine, disease modelling, and the role of research in expanding the frontiers of medical knowledge.

  • Ryan Hsieh

    Undergraduate Student

    I am in the third year of the Medical Sciences undergraduate program. I hope to pursue a career in medicine and explore my interests through research.

Alumni

  • Gemma Barber

    SRTP Student (2022-2023)

  • Suriya Kumaresan

    Postdoctoral Associate (2023)

  • Samuel Yeung

    Undergraduate work-study student (2023)

  • Shayan

    Grade 12 high school student (2022)

  • Matthew Wang

    4th year undergrad student (2023)

  • Foram Nail

    4th year undergrad student (2023)

  • Apple Geng

    4th year undergrad student (2022)

  • Mahima Bijji

    SRTP student (2022)

Lab photos

  • Holiday lunch, December 2023

  • Summer BBQ, July 2023

  • Holiday lunch, December 2022